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Post splenectomy ( changes in blood, complications, vaccines. antibiotics)

Author:Lengyel J.
on 28 Aug, 2007

Last edited by: Lengyel J. on 12 Oct, 2007
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Post splenectomy what can you expect?
 
 
 
Blood changes
RBC’s- morphology changes to include the appearance of Howell-Jolly bodies and Pappenheimer granules. Occasional erythroblasts
 
WBC’s- increased.  There is a marked left shift in the differential count
 
Platelets – normally the spleen pools 1/3 of platelets. Rise post splenectomy >1000 x109/l. Peaks at 7-14 days
 
 
Complications
 
The usual blurb about
            Early – bleeding (primary/ reactionary)
                        Respiratory complications esp with open
                         
Intermediate
      • Collections
      • Wound infection
      • DVT / PE
      • Thrombo prophylaxis is indicated to cover the thrombocytosis that occurs. BUT there is no indication for extended thrombosis prophylaxis after splenectomy in patients with HS.
 
            Late – covered in vaccines and antibiotics below
 
 
 
 
 
Vaccines and antibiotics
Vaccinations
            Pneumovax
Haemophilus Influenza type b vaccine (HiB)
Meningococcal Group C conjugate vaccine
Influenza immunisation
 
Antibiotics
Life long prophylactic antibiotics are still recommended (oral Phenoxymethylpenicillin or Erythromycin)
 
 

The British Committee for Standards in Haematology (BCSH) is a sub-committee of the British Society for Haematology (BSH). The primary purpose of the BCSH is to provide haematologists with up to date advice on the diagnosis and treatment of haematological disease by the production of evidence based guidelines using a well defined BCSH process.

 
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